Allergosan from Sopharma is an antiallergic drug used for seasonal allergic rhinitis (hay fever) and conjunctivitis, skin allergic reactions (rash, itching, insect bites, dermographism, urticaria and contact dermatitis), as well as drug and food allergies. Each tablet contains 25 mg of the active substance chloropyramine hydrochloride.

International Nonproprietary Name

Chloropyramine

Dosage form

Film-coated tablets

Compound

One tablet contains

• active ingredient - chloropyramine hydrochloride 25 mg,
• Excipients: lactose monohydrate; wheat starch; microcrystalline cellulose; sodium carmellose; talc; magnesium stearate; colloidal silicon dioxide, anhydrous
• Shell composition: main copolymer, butyl methacrylate; polysorbate 80, gelatin; gum arabic, spray-dried; talc, titanium dioxide (E171), sucrose, macrogol 6000, glycerol

Indications for use

• seasonal allergic rhinitis, conjunctivitis
• urticaria, pruritic dermatosis, contact dermatitis, insect bites, dermographism
• drug and food allergies

It should be taken into account that when taken orally, chloropyramine exhibits a pronounced sedative effect.

Method of administration and dosage

The tablets are taken whole, during meals, with water.

Adults and adolescents over 14 years of age: 1 tablet (25 mg) 3-4 times a day.

The maximum daily dose is 2 mg/kg b.w. In case of anaphylactic shock or acute and severe allergic reactions, treatment should begin with slow intravenous administration of the injection solution, after which it is possible to switch to intramuscular administration, followed, at the first opportunity, by oral administration.

In elderly patients (over 65 years old) and debilitated patients, the use of the drug requires special caution due to the manifestation of increased sensitivity to antihistamines in relation to their side effects.

In case of liver dysfunction, a dose reduction may be required due to a decrease in the metabolism of the active component of the drug in liver diseases.

In case of impaired renal function, it may be necessary to change the regimen of taking the drug and reduce the dose due to the fact that the active component is mainly excreted through the kidneys.

Duration of treatment

The duration of treatment depends on the type and severity of symptoms.

If Allergosan is ineffective in the first 2-3 days, it is necessary to consider using drugs from other groups.

Side effects

Adverse reactions are presented according to the organ-class system and frequency. Frequency is defined as: very common (≥ 1/10), common (≥ 1/100 to <1/10), uncommon (≥ 1/1,000 to <1/100), rare (≥ 1/10,000 to <1/1,000), very rare (< 1/10,000), not known (cannot be estimated from the available data).

Contraindications

• hypersensitivity to the active substance or to any of the
• auxiliary substances of the drug, to other derivatives of ethylenediamine, chloropyramine
• asthma attack
• pregnancy and lactation period
• pyloroduodenal stenosis
• diabetes mellitus
• hereditary lactose intolerance, fructose intolerance, lactase deficiency of the enzyme Lapp-lactase, glucose-galactose malabsorption, sucrase-isomaltase deficiency
• gastric ulcer and duodenal ulcer in the acute phase
• closed-angle glaucoma
• children under 14 years of age
• prostatic hypertrophy

Storage conditions

Store in the original packaging, in a dry and dark place, at a temperature not exceeding 25 C.

Keep out of reach of children!